What is Tetanus?

What is Tetanus? Clostridium tetani cause Tetanus. Which is a gram-positive anaerobic drumstick shaped bacteria like, This notice the rounded ends? That are spores giving the bacteria a drumstick like an appearance? What is the reservoir of the bacteria? That is where the bacteria are stored in nature. It is stored in the soil next to the incubation period of Stiegler's. It is 6 to 10 days. But it can vary significantly from a few days to several months next. What is the mode of transmission of Tetanus? Tetanus is spread by contamination of wounds next to remember that. Tetanus toxin is the second most lethal toxin in the world guess. What is the deadliest poison in the world is bottling abduction next what is the little those are signals, it is 0.1 milligram and Tetanus and symptoms of Tetanus?

Symptoms:

Next, what is the mechanism of action of the tetanus toxin after, We get an open wound or cut, the tetanus toxin enters our body? That wound from the damage the toxin enters the local neurons wire. Which the toxin travels retrograde until it finally inches the spinal cord in the spinal cord, the toxins accumulate. Till the inhibitory interneurons and inhibits it, we will get back to this point a little. While later found Nepal now the inhibition of the inhibitory interneurons leads to excitation of the autonomic. The motor neuron, the excitation of the autonomic nerves leads to blood pressure and heart rate alteration. Simultaneously, the motor neuron's excitation leads to several most severe muscle Tetanus and symptoms of Tetanus. That's contractions all over the body. Different names know these muscle contractions.

According to the muscles, they affect when the muscles contract contractions occur in the muscles of mastication. It is called Christmas. It is also known as an extended job as the patient cannot open his or her mouth. When the muscle contractions occur in a Bosch's muscle, it is called off this toe to the nose. Like this, this is a portrait of a soldier dying of thickness. When the muscle contractions occur in the muscles of facial expression, it is called a recessed sardonically—this next for those of you who wish to know the exact mechanism Tetanus and symptoms of Tetanus.

Transmission in the neuron:

How the detail of toxin inhibits the inhibitory interneurons. I will go into a bit more detail. The line diagram on the left side is that of a normal human being. At the same time, the line diagram on the right side belongs to a person with giddiness. So coming to the average human being side, the neurons block the transmission in the neuron. So the neurotransmitters are not released from the neuron resulting in muscle relaxation. But in a patient with thickness, the tetanus toxin blocks the inhibitory interneurons.

 So there is no inhibition of the neuron resulting in chronic excitation of the muscle. The muscle contractions occur; finally, we come to the prevention of technology. That is the post-exposure prophylaxis. Here we discussed what the steps to be taken are then we get an open wound. So we make a table on one side are the scars. Less than six hours old clean and non-penetrating and have negligible tissue damage on the other side are all the different types of things. So in a patient who has received complete scores of the oxide in the last five years.

Toxoid:

Nothing needs to be given in both the killers in a patient. Who has received a complete toxoid course in the last five to ten years a single dose of tetanus toxoid? Which needs to be given in both the cases for those who have received more than ten years ago. A single PT needs to be shown in the first case and a single TT dose plus human tetanus immune glory. It means to be given in the second case, finally, for those who have never received a tetanus vaccine.

Whose vaccination status in our is unknown toxoid complete course needs to be given in the first hit. Toxoid entire procedure, along with human business immunoglobulin, is to be shown in the second case. Finally, what is the minimum antitoxin level needed to be present in our body to prevent the statement? It is 0.1 international units per ml. Lastly, remember there is no herd immunity integral. That is, immunization of one person does not prevent infection in another person.